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Neuroendocrine Cancer Community

Stomach NENs

Jun 28, 2021

Stomach NENs are rare and account for less than 2% of all stomach cancers. Of those that occur, there are 3 key types – potentially 4*:
1️⃣ Type 1: The most common (70-80%) is usually quite small (less than 10mm) and may be multiple, it is rarely aggressive, usually well differentiated and unlikely to spread to other parts of the body (metastasise). May be associated with Atrophic and / or Auto-immune Gastritis and / or H.Pylori infection
2️⃣ Type II: Approximately 7-10%, as in Type I it is usually small and multiple, usually slow to grow, well-differentiated and unlikely to spread but the possibility is higher than with Type 1. May be associated with Zollinger Ellison Syndrome (ZES) and / or MEN1
3️⃣ Type III: approximately 20%, usually a solitary, larger lesion than seen in Types I & II (2 or more centimetres). It has well- or poorly differentiated cells, grows more rapidly than Type I or II and is more likely to spread (metastasise)
*Some experts suggest formally sub-dividing Type III according to cancer cell differentiation – i.e. well or poorly differentiated.
Find out more about Neuroendocrine Cancer of the Stomach ➡️